An underground market for unapproved weight-loss drugs is being driven by TikTok fitness influencers and sellers on communication apps, based on recent findings.
Retatrutide, which remains in clinical trials, is being advertised by online personalities for its supposed weight-reducing effects. Followers are urged to message these accounts directly for source information, while also obtaining promotional offers.
Additionally, a robust market exists on Telegram, where communities with thousands of members share “before and after” photos, administration instructions and claims of rapid British shipping. Vendors market the drug there before directing customers to WhatsApp for purchases.
Retatrutide is an experimental injection developed by American pharmaceutical company Eli Lilly. The drug affects three intestinal hormones – glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide and pancreatic hormone. Preliminary studies indicate it could help patients reduce up to a quarter of their body weight. Nicknamed the “triple G”, the drug is being hailed online as the successor to Ozempic.
However, physicians and pharmacists have warned that the distribution of what remains an unlicensed medication in the United Kingdom is worrisome and could lead to individuals injecting substances of unknown origin.
Several professionals said the popularity for retatrutide could be connected to the rising cost of approved weight loss products such as Mounjaro.
Marketing the unapproved drug on social media or Telegram is illegal in the UK, as it is an unapproved medication that must not be promoted or distributed for human use under the Human Medicines Regulations 2012.
Several content creators try to circumvent the rules by calling to the substance as a “research chemical” or citing it as “not for human consumption”. Retatrutide is not a controlled drug, but advertising and distribution can still violate medicines, advertising, and consumer regulations, risking penalties, prosecution or prison.
According to TikTok, the service has removed violative content and prohibited associated hashtags and search suggestions. The company said it was dedicated to keeping the service safe and investing in enhancing compliance measures.
Investigations also found groups with up to nine thousand participants selling retatrutide using the platform's integrated discovery tool, which operates like a online catalog. Typing “retatrutide” immediately displays channels with numerous of users, populated with photos of weight loss, positive reviews and detailed instructions for mixing or administering at residence.
After minutes of joining one community, a seller shared WhatsApp details, where the majority of purchases take place. The seller sent an instruction manual and guaranteed shipping within 48 hours. When questioned whether the substance was authentic, one seller responded: “You can’t be sure.” Another provided a photo of a supposed laboratory certificate. None asked about weight, medical conditions or previous experience.
Inside these communities, posts display dark colored parcels with postal service labels, stating to contain new batches. One message stated: “It took eight of us to load them this morning.”
Customers can select between powder vials, mixed at residence with purified liquid, or ready-to-use pens usually sold at 160 pounds for 20mg. When asked how much time a pen should last, sellers give contradictory answers ranging from a several days to “depends on your body”.
A representative for Telegram said it actively moderated dangerous content on its platform including material that encouraged the “misuse of controlled medications”. The company noted that it removed “millions of pieces of harmful content each day”.
“Individuals are injecting materials they can’t verify. Although the research behind retatrutide is sound, these online versions may not include what they claim,” stated a pharmacy expert, the director of pharmacy at Chemist4U.
A medical professional of Asda Online Doctor connected the increase in demand to recent price rises for authorized slimming drugs such as Mounjaro. “With costs rising, patients are turning to social media. But counterfeit treatments are highly dangerous. You can’t be certain what’s inside or whether the environment they were produced in was sterile,” she explained.
Her staff has already encountered patients injured by self-injection from unconfirmed suppliers. “We recognize the disappointment, but buying from Telegram or communication platforms is gambling with your well-being,” stated Wyllie. “These substances could be contaminated or improperly measured.”
A spokesperson from the pharmaceutical company said the substance was in phase 3 research studies and had not been reviewed or authorized by any regulatory agency anywhere in the world. “Consequently at this time no one can market [it] for personal consumption,” they said, adding that any product “falsely representing itself as a company experimental product not yet authorized … may expose patients to possibly serious health risks”.
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